vicissitude

Từ điển Oxford Learners Wordfinder Dictionary

noun

1. a variation in circumstances or fortune at different times in your life or in the development of something
- the project was subject to the usual vicissitudes of exploratory research
• Hypernyms:
variation, fluctuation
2. mutability in life or nature (especially successive alternation from one condition to another)
• Hypernyms:
mutability, mutableness