rheumatism 
1. any painful disorder of the joints or muscles or connective tissues (Freq. 2) • Derivationally related forms: rheumatic • Hypernyms: disease 2. a chronic autoimmune disease with inflammation of the joints and marked deformities; something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that can lead to the destruction of all components of the joint • Syn: rheumatoid arthritis, atrophic arthritis • Derivationally related forms: rheumatic • Topics: virus • Hypernyms: arthritis, autoimmune disease, autoimmune disorder • Hyponyms: psoriatic arthritis, Still's disease, juvenile rheumatoid arthritis
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